标签归档：norbornene

OVA Norbornene Conjugate Cat. No. OV1-NB-1 1 mg修饰性聚乙二醇

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OVA Norbornene Conjugate

Cat. No. OV1-NB-1
Specification
Unit Size 1 mg
Price $385.00

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Description:

Norbornene OVA conjugate is one of Nanocs albumin bioconjugate that can go Click Chemistry. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Norbornene conjugated OVA can be used to react with thiol or tetrazine bearing molecules.

Product Specifications:

  • Form: Lyophilized powder or buffered solution
  • Color: Colorlessr
  • Reactive groups: Norbornene
  • Reactive to: Thiol, tetrazine, amine
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at 4-8 0C. Desiccate.
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PG4A-NB-10k , 4 arm Norbornene PEG

4 arm Norbornene PEG Cat. No. PG4A-NB-10k 10000 500 mg修饰性聚乙二醇

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4 arm Norbornene PEG

Cat. No. PG4A-NB-10k
Specification 10000
Unit Size 500 mg
Price $385.00

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Synonym: 4 arm PEG norbornene, 4 arm Norbornene PEG, 4 branched Norbornene PEG

Description:

4 Arm norbornene PEG is one of Nanocs thiol-ene Click Chemistry reactive PEG derivatives that can be used for hydrogel synthesis, nanoparticle modification and new polymer synthesis. Norbornene is an excellent dienophile that can react with thiol group through thiol-ene Michael addition Click Chemistry reaction. It is also an ideal dienophile that can react rapidly and specifically with tetrazine through strain-promoted cycloaddition (1,2). Nanocs provides a number of norbornene functional PEGs that can react with various functional groups. Resulted norbornene group can be used to react with thiol or tetrazine rapidly  in aqueous solution.

Product Specification:

  • Form: Solid powder
  • Color: White
  • Solubility: Soluble in water
  • Reactive to: Thiol (-SH)
  • Purity: >95%

Storage:

  • Store at -20 0C.

References:

  1. Neal K.Devaraj, et al Bioconjug Chem. 2008, 19(12):2297-2299
  2. M.  K. Narayanam, et al Chem Sci, 2016, 7, 1257-1261

Click here to see hundreds publications using our products.

Norbornene PEG NHS Cat. No. PG2-NBNS-5k 5000 Da 25 mg修饰性聚乙二醇

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Norbornene PEG NHS

Cat. No. PG2-NBNS-5k
Specification 5000 Da
Unit Size 25 mg
Price $325.00

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Synonym: NHS PEG Norbornene, Norbornene PEG5000 NHS, NHS PEG5000 Norbornene

Description:

Norbornene PEG NHS is one of Nanocs Click Chemistry PEG Reagents that have a Norbornene group on one end of PEG chain and a succinimidyl NHS group on the other PEG terminus. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Meanwhile, NHS group  allows conjugation of Norbornene group to various molecules via their amine groups. Resulted Norbornene group thus can participate various Click Chemistry reactions.  PEG linker between Norbornene and NHS offers good water solubility, better stability or flexible linker structure.

Product Specifications:

  • Form: Solid powder
  • Color: White
  • Solubility: Soluble in water
  • Reactive groups: Norbornene, NHS
  • Reactive to: Thiol, tetrazine, amine
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at -20 0C. Desiccate.
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PG4A-NB-10k , 4 arm Norbornene PEG

Norbornene PEG Biotin Cat. No. PG2-BNNB-5k 5000 Da 25 mg修饰性聚乙二醇

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Norbornene PEG Biotin

Cat. No. PG2-BNNB-5k
Specification 5000 Da
Unit Size 25 mg
Price $325.00

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Synonym: Biotin PEG Norbornene, Norbornene PEG5000 Biotin, Biotin PEG5000 Norbornene

Description:

Norbornene PEG Biotin is one of Nanocs Click Chemistry PEG Reagents that have a Norbornene group on one end of PEG chain and a biotin tag on the other PEG terminus. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Meanwhile, biotin tag  can bind to avidin or streptavidin with high affinity. Biotin PEG Norbornene can participate various Click Chemistry reactions.  PEG linker between Norbornene and Biotin offers good water solubility, better stability or flexible linker structure.

Product Specifications:

  • Form: Solid powder
  • Color: White
  • Solubility: Soluble in water
  • Reactive groups: Norbornene, Biotin
  • Reactive to: Thiol, tetrazine, amine
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at -20 0C. Desiccate.

Norbornene PEG Amine Cat. No. PG2-AMNB-5k 5000 Da 25 mg修饰性聚乙二醇

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Norbornene PEG Amine

Cat. No. PG2-AMNB-5k
Specification 5000 Da
Unit Size 25 mg
Price $325.00

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Synonym: Amine PEG Norbornene, Norbornene PEG NH2, Norbornene PEG5000 Amine, Amino PEG5000 Norbornene

Description:

Norbornene PEG Amine (Norbornene PEG NH2) is one of Nanocs Click Chemistry PEG Reagents that have a Norbornene group on one end of PEG chain and an amine group on the other PEG terminus. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Meanwhile, amine group  allows conjugation of various molecules  to  PEG norbornene. PEG linker between Norbornene and amine offers good water solubility, better stability or flexible linker structure.

Product Specifications:

  • Form: Solid powder
  • Color: White
  • Solubility: Soluble in water
  • Reactive groups: Norbornene, amine
  • Reactive to: Thiol, tetrazine
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at -20 0C. Desiccate.
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PG4A-NB-10k , 4 arm Norbornene PEG

Norbornene PEG Acid Cat. No. PG2-CANB-5k 5000 Da 25 mg修饰性聚乙二醇

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Norbornene PEG Acid

Cat. No. PG2-CANB-5k
Specification 5000 Da
Unit Size 25 mg
Price $325.00

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Synonym: COOH PEG Norbornene, Norbornene PEG5000 Acid, Norbornene PEG COOH

Description:

Norbornene PEG Acid (Norbornene PEG COOH) is one of Nanocs Click Chemistry PEG Reagents that have a Norbornene group on one end of PEG chain and a carboxylic acid group (-COOH) on the other PEG terminus. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Meanwhile, COOH group  allows conjugation of Norbornene group to various molecules via their amine groups. Resulted Norbornene group thus can participate various Click Chemistry reactions.  PEG linker between Norbornene and COOH offers good water solubility, better stability or flexible linker structure.

Product Specifications:

  • Form: Solid powder
  • Color: White
  • Solubility: Soluble in water
  • Reactive groups: Norbornene, COOH
  • Reactive to: Thiol, tetrazine, amine
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at -20 0C. Desiccate.
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PG4A-NB-10k , 4 arm Norbornene PEG

Norbornene PEG FITC Cat. No. PG2-FCNB-5k 5000 Da 5 mg修饰性聚乙二醇

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Norbornene PEG FITC

Cat. No. PG2-FCNB-5k
Specification 5000 Da
Unit Size 5 mg
Price $325.00

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Synonym: FITC PEG Norbornene, Norbornene PEG Fluorescein, FITC PEG5000 Norbornene

Description:

Norbornene PEG FITC is one of Nanocs fluorescent Click Chemistry PEG Reagents that have a Norbornene group on one end of PEG chain and a fluorescein dye molecule the other PEG terminus. Norbornene is a strain-promoted dienophile that has been used in thiol-ene click chemistry to react with thiols. It also an excellent Click Chemistry reagent used in tetrazine-norbornene cycloaddition.  Meanwhile, FITC dye gives strong green fluorescence upon excited at 490 nm. Fluorescein PEG Norbornene thus can be easily detected with fluorescent instruments. PEG linker between Norbornene and FITC offers good water solubility, better stability or flexible linker structure.

Product Specifications:

  • Form: Solid powder
  • Color: Yellow
  • Solubility: Soluble in water
  • Reactive groups: Norbornene
  • Reactive to: Thiol, tetrazine, amine
  • Ex/Em wavelength: 495 nm/515 nm
  • Purity: >95%
  • Applications: Thiol-ene and tetrazine-norbornene  click chemistry

Storage:

  • Store at -20 0C. Protect from light.
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PG4A-NB-10k , 4 arm Norbornene PEG