标签归档：cyclohexane

LC-SMCC (succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate)) Cat. No. SMCC-LC-1 MW 444.78 100 mg修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

LC-SMCC (succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxy-(6-amidocaproate))

Cat. No. SMCC-LC-1
Specification MW 444.78
Unit Size 100 mg
Price $485.00

Qty Add to Cart

Name: LC-SMCC, Long chain-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate

Synonym: LC-SMCC, long chain 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester

Description:

LC-SMCC, also called Long chain succinimidyl cyclohexane Maleimide, is one of  Nanocs' amine and sulfhydryl reactive crosslinkers. This crossliner is non-cleavable and membrane permeable. It contains an amine reactive NHS ester and a sulfhydryl reactive maleimide group. Compared to other maleimide NHS ester, LC-SMCC has higher stability in aqueous solution because of its cyclohexane bridge. NHS esters react with primary amines at pH 7-9 while the maleimide group reacts with available thiol or sulfhydryl at pH 6.5~7.5 to form stable thioether bonds.

Physical Properties of SMCC:

  • Appearance: Off-white/white solid;
  • Molecular formula: C22H29N3O7;
  • Molecular weight: 447.48;
  • Reactive to: Sulfhydryl and primary amine group;
  • Purity: >95%
  • Soluble in DMF or DMSO;

Storage Conditions of LC-SMCC:

  • LC-SMCC should be stored at -20 0C or lower. Desiccate. Avoid frequent thaw and freeze.