2 Arm/Branched PEG NHS

Description:

2 arm PEG derivatives have two PEG branches with one or two functional groups that can be used to modify proteins, peptides and other materials via their functional groups. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. .

Physical Properties:

• Off-white/white solid or viscous liquid depends on molecule weight;
• Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

• Store at -20 ⁰C, desiccated Protect from light. Avoid frequent thaw and freeze.

2 Arm/Branched PEG NHS

Synonym: 2 arm NHS PEG, 2 branched PEG  NHS, Y-shaped PEG NHS, 2 arm PEG succinimidyl ester

Description:

2 arm PEG NHS is one of  Nanocs reactive multi-arm PEG derivatives that have multiple succinimidyl NHS groups that can be used to modify proteins, peptides and other materials via their amino groups. NHS reacts with primary amine groups rapidly at alkaline pH to form stable amide bonds. 2 arm NHS PEG has been used for hydrogel formation, nanoparticle surface modification and many other applications. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces. .

Physical Properties:

• Form: Solid
• Color: White
• Solubility: Soluble in water
• Reactive group: Succinimyl ester  (NHS)
• Reactive to: Primary amine (-NH2)
• Purity: >95%
• Applications: Hydrogel synthesis, surface modification

Storage Conditions:

• Store at -20 ⁰C. Desiccate. Avoid frequent thaw and freeze.

References:

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