标签归档：aldehyde

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-30k 30000 Da 100 mg修饰性聚乙二醇

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PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-30k PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-30k 30000 Da 100 mg
Specification 30000 Da
Unit Size 100 mg
Price $485.00

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PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-40k 40000 Da 200 mg修饰性聚乙二醇

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PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-40k PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-40k 40000 Da 200 mg
Specification 40000 Da
Unit Size 200 mg
Price $485.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-350 350 Da 100 mg修饰性聚乙二醇

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PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-350 PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-350 350 Da 100 mg
Specification 350 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-550 550 Da 100 mg修饰性聚乙二醇

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PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-550 PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-550 550 Da 100 mg
Specification 550 Da
Unit Size 100 mg
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-750 750 Da 100 mg修饰性聚乙二醇

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PEG Aldehyde, mPEG-CH2CHO

Cat. No. PG1-AL-750 PEG Aldehyde, mPEG-CH2CHO Cat. No. PG1-AL-750 750 Da 100 mg
Specification 750 Da
Unit Size 100 mg
Price $385.00

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PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Dextran, Aldehyde Functional Cat. No. DX5-AL-1 5000 Da 25 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX5-AL-1
Specification 5000 Da
Unit Size 25 mg
Price $325.00

Qty Add to Cart

Similar names: Dextran aldehyde, Dextran-CHO

Description:

Aldehyde functionalized dextrans (Dextran-CHO) are capable of reacting with amine or hydrazide groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: Aldehyde
  • Reactive to: Primary amine, hydrazide, hydroxyamine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C.

Dextran, Aldehyde Functional Cat. No. DX10-AL-1 10000 Da 50 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX10-AL-1
Specification 10000 Da
Unit Size 50 mg
Price $385.00

Qty Add to Cart

Aldehyde functional Dextran

Description:

Aldehyde functionalized dextrans are capable of reacting with primary amine groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • 1~50 aldehyde groups on each dextran molecule depends on molecular weight of dextran.
  • Dextran conjugates provided in dried powder form;

Storage Conditions:

  • Store at -20 0C.

Dextran, Aldehyde Functional Cat. No. DX40-AL-1 40000 Da 50 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX40-AL-1
Specification 40000 Da
Unit Size 50 mg
Price $385.00

Qty Add to Cart

Similar names: Dextran aldehyde, Dextran-CHO

Description:

Aldehyde functionalized dextrans (Dextran-CHO) are capable of reacting with amine or hydrazide groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: Aldehyde
  • Reactive to: Primary amine, hydrazide, hydroxyamine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C.
Related Products
DX40-NS-1 , NHS activated Dextran

Dextran, Aldehyde Functional Cat. No. DX70-AL-1 70000 Da 50 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX70-AL-1
Specification 70000 Da
Unit Size 50 mg
Price $385.00

Qty Add to Cart

Similar names: Dextran aldehyde, Dextran-CHO

Description:

Aldehyde functionalized dextrans (Dextran-CHO) are capable of reacting with amine or hydrazide groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: Aldehyde
  • Reactive to: Primary amine, hydrazide, hydroxyamine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C.

Dextran, Aldehyde Functional Cat. No. DX500-AL-1 500 kDa 50 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX500-AL-1
Specification 500 kDa
Unit Size 50 mg
Price $385.00

Qty Add to Cart

Similar names: Dextran aldehyde, Dextran-CHO

Description:

Aldehyde functionalized dextrans (Dextran-CHO) are capable of reacting with amine or hydrazide groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: Aldehyde
  • Reactive to: Primary amine, hydrazide, hydroxyamine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C.

Dextran, Aldehyde Functional Cat. No. DX2000-AL-1 2000 kDa 100 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX2000-AL-1
Specification 2000 kDa
Unit Size 100 mg
Price $385.00

Qty Add to Cart

Similar names: Dextran aldehyde, Dextran-CHO

Description:

Aldehyde functionalized dextrans (Dextran-CHO) are capable of reacting with amine or hydrazide groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: Aldehyde
  • Reactive to: Primary amine, hydrazide, hydroxyamine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C.
Related Products
DX10-ML-1 , Dextran, Maleimide Functional
DX40-ML-1 , Dextran, Maleimide Functional
DX70-ML-1 , Dextran, Maleimide Functional

Dextran, Aldehyde Functional Cat. No. DX3-AL-1 3000 Da 5 mg修饰性聚乙二醇

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Dextran, Aldehyde Functional

Cat. No. DX3-AL-1
Specification 3000 Da
Unit Size 5 mg
Price $485.00

Qty Add to Cart

Similar names: Dextran aldehyde, Dextran-CHO

Description:

Aldehyde functionalized dextrans (Dextran-CHO) are capable of reacting with amine or hydrazide groups via so called Schiff reaction. Nanocs provides a variety of chemically functionalized and bioconjugated dextran products with molecular weight ranged from 3,000 Da to 2,000 KDa. These functional dextrans were purified by size-exclusion chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Dextrans modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized dextran products for your special needs.

Specifications:

  • Form: Powder
  • Color: White to off-white
  • Functional groups: Aldehyde
  • Reactive to: Primary amine, hydrazide, hydroxyamine
  • Solubility: Soluble in water

Storage Conditions:

  • Store at -20 0C.
Related Products
DX5-AM-1 , Dextran, Amine Functional
DX10-AM-1 , Dextran, Amine Functional
DX40-AM-1 , Dextran, Amine Functional
DX70-AM-1 , Dextran, Amine Functional
DX500-AM-1 , Dextran, Amine Functional
DX2000-AM-1 , Dextran, Amine Functional
DX3-AM-1 , Dextran, Amine Functional

Aldehyde Functional Glass Slides Cat. No. GS-AL-25 20 pk修饰性聚乙二醇

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Aldehyde Functional Glass Slides

Cat. No. GS-AL-25
Specification
Unit Size 20 pk
Price $385.00

Qty Add to Cart

Aldehyde Functional Glass Slides

Description

Aldehyde functionalized glass slides are one of Nanocs premier functional glass products. Nanocs provides various surface functionalized glass slides and coverslips that can be used to attach biomolecules on top of them. Functional groups and coatings include amine, carboxylic acid, aldehyde, epoxide, biotin, streptavidin, NTA, maleimide, disulfide, azide, alkyne, as well as poly-D-lysine and poly-L-lysine. Nanocs glass slides and coverslips were fabricated with unique coating technologies to ensure their high reactivity, uniformity and low non-specific absorption. These glass slides and coverslips can be used for microarray fabrication, cell culture growth and various confocal microscope work.

Nanocs aldehyde functional glass Specifications:

  • Surface functionality: Aldehyde (-CHO);
  • Glass size: 25x75x1.1 mm;
  • Aldehyde density: 50~100 umol CHO/cm2.

Ficoll, aldehyde functional Cat. No. FC70-AL-1 70 kD 10 mg修饰性聚乙二醇

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Ficoll, aldehyde functional

Cat. No. FC70-AL-1
Specification 70 kD
Unit Size 10 mg
Price $485.00

Qty Add to Cart

Description:

Nanocs provides a variety of chemically functionalized and bioconjugated Ficoll products with molecular weight ranged from 70 kDa to 400 KDa. These functional ficoll polymers were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Ficolls are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Ficolls modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized ficoll products for your special needs.

Specifications:

  • 1~30 functional groups on each ficoll molecule.
  • Ficoll conjugates provided either in water solution and dried powder;

Storage Conditions:

  • Store at 4 0C. Protect from light.

Ficoll, aldehyde functional Cat. No. FC400-AL-1 400 kD 10 mg修饰性聚乙二醇

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Ficoll, aldehyde functional

Cat. No. FC400-AL-1
Specification 400 kD
Unit Size 10 mg
Price $485.00

Qty Add to Cart

Description:

Nanocs provides a variety of chemically functionalized and bioconjugated Ficoll products with molecular weight ranged from 70 kDa to 400 KDa. These functional ficoll polymers were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

Ficolls are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. Ficolls modified with dyes and other biomolecules have been successfully used as long-term tracers for live cells. Nanocs also provides customerized ficoll products for your special needs.

Specifications:

  • 1~30 functional groups on each ficoll molecule.
  • Ficoll conjugates provided either in water solution and dried powder;

Storage Conditions:

  • Store at 4 0C. Protect from light.

Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-5k 5000 Da 1 g修饰性聚乙二醇

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Aldehyde PEG Aldehyde,CHO-PEG-CHO

Cat. No. PG2-AL-5k Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-5k 5000 Da 1 g
Specification 5000 Da
Unit Size 1 g
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-3k 3400 Da 1 g修饰性聚乙二醇

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Aldehyde PEG Aldehyde,CHO-PEG-CHO

Cat. No. PG2-AL-3k Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-3k 3400 Da 1 g
Specification 3400 Da
Unit Size 1 g
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-2k 2000 Da 1 g修饰性聚乙二醇

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上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Aldehyde PEG Aldehyde,CHO-PEG-CHO

Cat. No. PG2-AL-2k Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-2k 2000 Da 1 g
Specification 2000 Da
Unit Size 1 g
Price $485.00

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PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet

Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-10k 10000 Da 1 g修饰性聚乙二醇

发表于由

上海金畔生物科技有限公司提供各种分子量和基团修饰性聚乙二醇定制服务。

Aldehyde PEG Aldehyde,CHO-PEG-CHO

Cat. No. PG2-AL-10k Aldehyde PEG Aldehyde,CHO-PEG-CHO Cat. No. PG2-AL-10k 10000 Da 1 g
Specification 10000 Da
Unit Size 1 g
Price $385.00

Qty Add to Cart

PEG Aldehyde Description:

Aldeyde PEG is an amine reactive PEG derivative that can be used to modify biomolecules via available amine groups. The reaction between aldehyde group with ε-amine of lysine residues and the α-amine at the N-terminus produces an intermediate Schiff base. Further reduction with hydride will form a stable C-N bond. PEG aldehydes react with amine groups at a pH of from 5.5 to 9.5. Higher pH will result in multiple Pegylation with both terminal and lysine groups. Aldehyde PEG is a commonly used PEG reagent for n-terminus pegylation in proteins or peptides.

Physical Properties:

  • Off-white/white solid or viscous liquid depends on molecule weight;
  • Soluble in regular aqeous solution as well as most organic solvents;

Storage Conditions:

  • Store at -20 0C

Reaction Procedures:

Generally, a 10- to 50-fold molar excess of PEG aldehyde over the amount of amine-containing material results in sufficient conjugation.

Materials Required:

  • Pegylation buffer: Amine-free aqueous buffer, pH 6~8.5.
  • PEG aldehyde stock solution: 100 mg in 1 mL conjugation buffer.
  • Washing solution: Distilled water or any aqueous buffer.

Reaction Steps:

Dissolve targeted materials in pegylation buffer. Estimate the concentration of primary amine groups on the targeted materials. Add PEG aldehyde stock solution to the targeted conjugation materials with the final concentration keep at least 10 mg/mL. Allow mixture agitates at room temperature for 2~4 hrs at room temperature or overnight 4 0C. After reaction, C=N bond can be reduced by sodium borohydride. Conjugate can be purified either by size exclusion chromatography or dialysis.

Documents
  • SDS
  • DataSheet