美国戴安Dionex Acclaim Mixed-Mode WAX-1 LC Column 液相色谱


美国戴安Dionex Acclaim Mixed-Mode WAX-1 LC Column 液相色谱

简要描述:

戴安公司生产的仪器主要有离子色谱仪、高效液相色谱仪、快速溶剂萃取仪和氨基酸直接分析仪。其中离子色谱仪凭借着雄厚的技术优势和方法已广泛地应用于各个领域,其市场占有率达80%。与离子色谱相关的文章有90%均出自戴安公司生产的离子色谱仪。   
戴安公司的快速溶剂萃取仪15分钟之内仅用15毫升溶剂既可完成对10g样品的萃取,该技术已在环境、药物、食品和聚合物工业等领域得到广泛应用。

型号 074188

美国戴安Dionex Acclaim Mixed-Mode WCX-1 LC Column 液相色谱柱

Acclaim Mixed-Mode WAX-1 LC Column 

Reversed-Phase and Weak Anion-Exchange Properties on a Single Column

美国戴安Dionex Acclaim Mixed-Mode WAX-1 LC Column 液相色谱

The novel column chemistry of the Acclaim® Mixed-Mode WAX-1 results in a multimode separation mechanism including hydrophobic, anion-exchange, and cation-exclusion interactions. Consequently, retention of basic, neutral, and acidic molecules can be either independently or concurrently adjusted by changing ionic strength, pH, and organic solvent content in the phase.

  • Adjustable selectivity
  • Selectivity orthogonal to reversed-phase (RP) columns
  • Ideal selectivity for anionic molecules
  • Simultaneous separation of acidic, basic, and neutral molecules
  • Multimode retention mechanisms: reversed- and normal phase, anion-exchange, cation-exclusion, and HILIC modes

The Acclaim Mixed-Mode WAX-1 column combines hydrophobic and anion-exchange characteristics, on a 5 μm high-purity, porous silica with 120-Å diameter pores. Because of this unique chemistry, the Acclaim Mixed-Mode WAX-1 column also provides complimentary selectivity to C18 reversed-phase columns.

Hydrophilic organic acids are often difficult to separate with common RP columns, since hydrophobic retention alone is inadequate to differentiate molecules with similar hydrophobicities. This can be overcome using the Acclaim Mixed-Mode WAX-1 column; it provides sufficient retention, and ideal selectivity for a variety of anionic molecules, even for weakly charged molecules.

Multi-Mode Separation Mechanism

Retention of basic, neutral and acidic molecules can be either independently or concurrently adjusted by changing ionic strength, pH, and organic solvents content in the phase. The presence of anion-exchange functionality control through electrostatic attraction (anions), repulsion (cations). The alkyl chain controls separation by hydrophobic interaction.

A broad range of samples in the pharmaceuticalfood and beverage and chemical industries can be separated. Separation of basic active ingredients and its counter-ion can be simultaneously determined, as well as separation of ingredients containing basic, neutral, and acidic ingredients.

技术参数:

Acclaim Mixed-Mode WAX-1 Columns: A simple solution to difficult separations  Specifications
Column Chemistry Alkyl amine
Base silica Spherical, high-purity
Particle size 5 µm
Pore size 120 Å
Surface area 300 m2/g

订购信息:

Analytical Columns
Acclaim Mixed-Mode WAX-1, 3µm Analytical, (3.0 x 150mm) 070088
Acclaim Mixed-Mode WAX-1, 3µm Analytical, (3.0 x 50mm) 071908
Acclaim Mixed-Mode WAX-1, 3µm Analytical, (2.1 x 150mm) 070089
Acclaim Mixed-Mode WAX-1, 5 µm (4.6 x 150 mm) 064984
Acclaim Mixed-Mode WAX-1, 5 µm (4.6 x 250 mm) 064985
Acclaim Mixed-Mode WAX-1, 5 µm, 2.1 x 150 mm 067084

Guard Columns
Acclaim Mixed-Mode WAX-1, 5 µm Guard Cartridges (4.6 x 10 mm), 2 ea (use V-2 Holder) 069704
Acclaim Mixed-Mode WAX-1, 5µm Guards (3 x 10mm), 2ea, requires holder 069580 071909
Acclaim Mixed-Mode WAX-1, 5µm, Guards (2.1 x 10mm), 2 ea; requires holder 069580 069686
Acclaim SST Guard Cartridge Holder V-2 069580
Acclaim Guard Kit (Holder and coupler) V-2 069707
Guard to Analytical Column Coupler V-2 074188